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They can contain the wrong medicine, the wrong dose, or substances that have not been stored safely
Full safety data, including any rarer or longer-term effects, will be reviewed in detail by regulators such as the MHRA in the UK and the FDA in the US before any decision is made on licensing
& Holz, G
328 Although setbacks occurred in the phase II study, the combination of ADI-PEG-20 and mFOLFOX6 chemotherapy regimen did not show a significant therapeutic advantage for hepatocellular carcinoma, 239 but there are a small number of subjects who benefit from this regimen
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